Can I call two methods in an if statement at the same time?

namespace UpOrDown
{
    public partial class Form1 : Form
    {
        public Form1()
        {
            InitializeComponent();
        }

        int score = 0;
        int wrong = 0;
        int highScore = 0;
        Random random = new Random();


        public void correctGuess()
        {
            score++;
            scoreCounterLabel.Text = score.ToString();
        }

        public void wrongGuess()
        {
            wrong++;
            wrongScore.Text = wrong.ToString();
        }

        public void gameOver()
        {
            highScore = score;
            highscoreScore.Text = highScore.ToString();
            MessageBox.Show("Game Over");
        }

        public void reset()
        {
            scoreCounterLabel.Text = "0";
            wrongScore.Text = "0";
            score = 0;
            wrong = 0;
        }

        private void upButton_Click(object sender, EventArgs e)
        {
            int randomNumber = random.Next(0, 10);

            if (randomNumber >= 5 && wrong <= 3)
            {
                correctGuess();
            }
            else
            {
                wrongGuess();
            }

            if (wrong == 3)
            {
                gameOver();
            }
        }

        private void downButton_Click(object sender, EventArgs e)
        {
            int randomNumber = random.Next(0, 10);

            if (randomNumber <= 5 && wrong <= 3)
            {
                correctGuess();
            }
            else
            {
                wrongGuess();
            }

            if (wrong == 3)
            {
                gameOver();
                reset();
            }
        }
    }
}